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Impact of fullerenol on cellular viability and reactive oxygen species (ROS) production in vitro. The percentage of viability in bEnd3, CTX <t>TNA2,</t> and BV2 cells is depicted in ( A ), while the level of ROS in bEnd3, CTX TNA2, and BV2 cells is shown in ( B ). Statistical significance is indicated by * p ≤ 0.05, in comparison to the control group and the group exposed solely to Aβ42.
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Impact of fullerenol on cellular viability and reactive oxygen species (ROS) production in vitro. The percentage of viability in bEnd3, CTX TNA2, and BV2 cells is depicted in ( A ), while the level of ROS in bEnd3, CTX TNA2, and BV2 cells is shown in ( B ). Statistical significance is indicated by * p ≤ 0.05, in comparison to the control group and the group exposed solely to Aβ42.

Journal: Antioxidants

Article Title: Distinctive Effects of Fullerene C 60 and Fullerenol C 60 (OH) 24 Nanoparticles on Histological, Molecular and Behavioral Hallmarks of Alzheimer’s Disease in APPswe/PS1E9 Mice

doi: 10.3390/antiox14070834

Figure Lengend Snippet: Impact of fullerenol on cellular viability and reactive oxygen species (ROS) production in vitro. The percentage of viability in bEnd3, CTX TNA2, and BV2 cells is depicted in ( A ), while the level of ROS in bEnd3, CTX TNA2, and BV2 cells is shown in ( B ). Statistical significance is indicated by * p ≤ 0.05, in comparison to the control group and the group exposed solely to Aβ42.

Article Snippet: CTX TNA2 cells are type 1 astrocytes (CRL-2006, ATCC, Manassas, VA, USA), bEnd.3 cells are mouse brain endothelial cells (CRL-2299, ATCC, Manassas, VA, USA), and BV2 cells are mouse microglial cell lines (ABC-TC212S, AcceGen, Fairfield, NJ, USA).

Techniques: In Vitro, Comparison, Control